RESUMO
Objectives: To find out sociodemographic characteristics ofChronic Suppurative Otitis Media (CSOM) in Bangladesh.Methods: It was a prospective study conducted in thedepartment of otolaryngology & Head Neck Surgery,Bangabandhu Sheikh Mujib Medical University (BSMMU) andDhaka Medical College Hospital (DMCH), Dhaka, fromSeptember 2010 to February 2011. Fifty cases were selectedby random sampling. A descriptive analysis was performed forclinical features and results were presented as mean ±standard deviation for quantitative variables and numbers(percentages) for qualitative variables.Results: In tubotympanic group, 51.61% patients belong to 21-30 years age group, whereas for atticoantral, 63.15% patientsbelong to 11-20 years age group. People living in rural area(66%) were more sufferers. Bilateral involvement is morecommon in tubotympanic type of disease & unilateralinvolvement was more common in atticoantral type of CSOM.Conclusion: CSOM is the most common chronic ear diseasein Bangladesh. It is more common in rural peoples ofyounger age group in poor socioeconomic classes with malepredominance. Medical and surgical options are limited, withside effects and risks, and sometimes are not successful ineliminating disease. There is an urgent need to focus in thearea of CSOM and hence prevent hearing loss.
RESUMO
Introduction: Diabetes mellitus is one of the five leadingcauses of death in the world.Objective: Our main goal is to estimate the effect of aqueousextract of Momordica charantia on blood glucose level inalloxan induced diabetic rats.Methodology: This experimental study was carried out atDepartment of pharmacology, Dhaka medical college, Dhakafrom July 2014 to June 2015 where the study was divided intotwo parts, Experiment-1 and Experiment-2. In Experiment-1include group A and group B. Experiment-2 include group C,group D and group E. Blood was collected from group A andgroup B on day 1 and day 15 and from group C,D and E onday 1,4 and 15 of experiment.Results: During the result in group-A (served as control andreceived normal rat diet for 14 days) the blood glucose levels(mean ± SD) were 4.90±0.50 mmol/L and 5.3±0.38mmol/L onday 1 and day 15 respectively. Percent inhibition was 4.8 andin group-B the blood glucose levels (mean ± SD) were5.00±0.36mmol/L and 5.05±0.32 mmol/L on day 1 and 15respectively. Also for in group C, the blood glucose levels(mean ± SD) were 5.31± 0.45 and 14.24±.51 on day 1 andday 15 respectively.Conclusion: From the analysis we can conclude that thataqueous extract of Momordica charantia has hypoglycaemiceffect, thus provide a rational for its use in development of newdrug require for treatment and prevention of complications ofdiabetes mellitus.